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TrialMind vs Covidence vs Rayyan

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TrialMind vs Covidence vs Rayyan: systematic review tools compared, from each company’s public pages, checked 2026-10-21
TrialMindKeiji AIAI agents for HEOR reviewsCovidence (Future Evidence Foundation)Systematic review production platformRayyanAI-assisted literature review platform
Best forHEOR reviews that must become HTA dossiers, with a reason per decisionCochrane-style reviews with dual human screening at a low per-review priceA free start and low seat prices, with AI screening on institutional plans
Review
AI screeningYes: Every abstract scored against criteriaPartly: ML sorting; dual human screening1Yes: ResearchPilot AI Reviewer2
AI data extractionYes: Tables linked to source papersYes: Suggested values linked to source text3Yes: Auto Extraction highlights source text2
Reason for every exclusionYes: Recorded reason for every decisionYes: Exclusion reasons captured by reviewers3Yes: AI decisions with reasoning notes2
PRISMA flow diagramYes: PRISMA-reported outputYes: Generated from review decisions3Yes: Generated automatically4
Synthesis and HTA
Indirect comparison or NMAYes: Bucher and other ITCs, documentedNo: Data moves to RevMan Web5Not stated publicly4
HTA dossier formatsYes: NICE, G-BA, CADTH, HAS, PBACNot stated publicly3Not stated publicly4
Access
Deployment and securityCloud or your environment; SOC 2, ISO 27001Browser-based; SSL and backups6SOC 2, ISO 27001, HIPAA, GDPR4
PricingQuote from Keiji AI$339 per review per year6Free plan; seats from $4.99/month7

From each company’s public pages, checked 2026-10-21. A dash means the company does not say.

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Sources · checked 2026-10-21

Product details come from each company’s public pages. Spotted something out of date? Tell us and we will correct it.

  1. Covidence: www.covidence.org/from-manual-to-machine-how-covidences-ml-is-streamlining-systematic-reviews/
  2. Rayyan: www.rayyan.ai/researchpilot
  3. Covidence: www.covidence.org/
  4. Rayyan: www.rayyan.ai/
  5. Covidence: www.cochrane.org/events/moving-data-covidence-revman-advantages-standardised-data-package
  6. Covidence: www.covidence.org/pricing/
  7. Rayyan: www.rayyan.ai/pricing