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TrialMind vs DistillerSR vs Nested Knowledge

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TrialMind vs DistillerSR vs Nested Knowledge: systematic review tools compared, from each company’s public pages, checked 2026-10-21
TrialMindKeiji AIAI agents for HEOR reviewsDistillerSR Inc.Literature review and evidence platformNested KnowledgeLiving review and meta-analysis software
Best forHEOR reviews that must become HTA dossiers, with a reason per decisionEnterprise review programs needing configurable AI screening and Part 11 controlsLiving reviews with built-in network meta-analysis and visual outputs
Review
AI screeningYes: Every abstract scored against criteriaYes: Generative AI Smart Screening1Yes: Robot Screener as second reviewer2
AI data extractionYes: Tables linked to source papersYes: Smart Evidence Extraction3Partly: Smart Tags extract PICO from abstracts4
Reason for every exclusionYes: Recorded reason for every decisionYes: Audit trail; AI explains decisions1No: Robot Screener gives no exclusion reasons2
PRISMA flow diagramYes: PRISMA-reported outputYes: Standard PRISMA reporting3Yes: Generated from AutoLit screening5
Synthesis and HTA
Indirect comparison or NMAYes: Bucher and other ITCs, documentedNot stated publicly3Yes: NMA with forest plots, SUCRA6
HTA dossier formatsYes: NICE, G-BA, CADTH, HAS, PBACNot stated publicly: Positioned for HEOR and CERs3Partly: Supports HTA; no dossier formats stated7
Access
Deployment and securityCloud or your environment; SOC 2, ISO 27001AWS; SOC 2 Type II, Part 118Browser-based; certifications not stated9
PricingQuote from Keiji AIQuote-based10From $295 per user per month11

From each company’s public pages, checked 2026-10-21. A dash means the company does not say.

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Sources · checked 2026-10-21

Product details come from each company’s public pages. Spotted something out of date? Tell us and we will correct it.

  1. DistillerSR: www.distillersr.com/products/distillersrai
  2. Nested Knowledge: about.nested-knowledge.com/docs/robot-screener/
  3. DistillerSR: www.distillersr.com/products/distillersr-systematic-review-software
  4. Nested Knowledge: about.nested-knowledge.com/docs/core-smart-tags/
  5. Nested Knowledge: about.nested-knowledge.com/features/
  6. Nested Knowledge: about.nested-knowledge.com/docs/explore-nma/
  7. Nested Knowledge: about.nested-knowledge.com/health-economics-and-outcomes-research/
  8. DistillerSR: www.distillersr.com/about/trust
  9. Nested Knowledge: about.nested-knowledge.com/docs/supported-platforms/
  10. DistillerSR: www.distillersr.com/pricing/corporate-and-government-pricing
  11. Nested Knowledge: about.nested-knowledge.com/pricing/