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TrialMind vs DistillerSR vs Rayyan

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TrialMind vs DistillerSR vs Rayyan: systematic review tools compared, from each company’s public pages, checked 2026-10-21
TrialMindKeiji AIAI agents for HEOR reviewsDistillerSR Inc.Literature review and evidence platformRayyanAI-assisted literature review platform
Best forHEOR reviews that must become HTA dossiers, with a reason per decisionEnterprise review programs needing configurable AI screening and Part 11 controlsA free start and low seat prices, with AI screening on institutional plans
Review
AI screeningYes: Every abstract scored against criteriaYes: Generative AI Smart Screening1Yes: ResearchPilot AI Reviewer2
AI data extractionYes: Tables linked to source papersYes: Smart Evidence Extraction3Yes: Auto Extraction highlights source text2
Reason for every exclusionYes: Recorded reason for every decisionYes: Audit trail; AI explains decisions1Yes: AI decisions with reasoning notes2
PRISMA flow diagramYes: PRISMA-reported outputYes: Standard PRISMA reporting3Yes: Generated automatically4
Synthesis and HTA
Indirect comparison or NMAYes: Bucher and other ITCs, documentedNot stated publicly3Not stated publicly4
HTA dossier formatsYes: NICE, G-BA, CADTH, HAS, PBACNot stated publicly: Positioned for HEOR and CERs3Not stated publicly4
Access
Deployment and securityCloud or your environment; SOC 2, ISO 27001AWS; SOC 2 Type II, Part 115SOC 2, ISO 27001, HIPAA, GDPR4
PricingQuote from Keiji AIQuote-based6Free plan; seats from $4.99/month7

From each company’s public pages, checked 2026-10-21. A dash means the company does not say.

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