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TrialMind vs Nested Knowledge vs Laser AI

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TrialMind vs Nested Knowledge vs Laser AI: systematic review tools compared, from each company’s public pages, checked 2026-10-21
TrialMindKeiji AIAI agents for HEOR reviewsNested KnowledgeLiving review and meta-analysis softwareEvidence PrimeAI tool for evidence synthesis
Best forHEOR reviews that must become HTA dossiers, with a reason per decisionLiving reviews with built-in network meta-analysis and visual outputsSource-linked extraction with a per-record history log
Review
AI screeningYes: Every abstract scored against criteriaYes: Robot Screener as second reviewer1Yes: Ranks records against inclusion criteria2
AI data extractionYes: Tables linked to source papersPartly: Smart Tags extract PICO from abstracts3Yes: Values linked to the PDF2
Reason for every exclusionYes: Recorded reason for every decisionNo: Robot Screener gives no exclusion reasons1Partly: Every decision logged, per-record history2
PRISMA flow diagramYes: PRISMA-reported outputYes: Generated from AutoLit screening4Yes: PRISMA and Cochrane compliant5
Synthesis and HTA
Indirect comparison or NMAYes: Bucher and other ITCs, documentedYes: NMA with forest plots, SUCRA6Not stated publicly2
HTA dossier formatsYes: NICE, G-BA, CADTH, HAS, PBACPartly: Supports HTA; no dossier formats stated7Not stated publicly: Audit-ready SLRs; no HTA formats5
Access
Deployment and securityCloud or your environment; SOC 2, ISO 27001Browser-based; certifications not stated8ISO 27001, SOC 2, FedRAMP9
PricingQuote from Keiji AIFrom $295 per user per month10$3,000 per project11

From each company’s public pages, checked 2026-10-21. A dash means the company does not say.

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Sources · checked 2026-10-21

Product details come from each company’s public pages. Spotted something out of date? Tell us and we will correct it.

  1. Nested Knowledge: about.nested-knowledge.com/docs/robot-screener/
  2. Laser AI: www.laser.ai/product
  3. Nested Knowledge: about.nested-knowledge.com/docs/core-smart-tags/
  4. Nested Knowledge: about.nested-knowledge.com/features/
  5. Laser AI: www.laser.ai/sectors/pharmaceutical-companies
  6. Nested Knowledge: about.nested-knowledge.com/docs/explore-nma/
  7. Nested Knowledge: about.nested-knowledge.com/health-economics-and-outcomes-research/
  8. Nested Knowledge: about.nested-knowledge.com/docs/supported-platforms/
  9. Laser AI: www.laser.ai/
  10. Nested Knowledge: about.nested-knowledge.com/pricing/
  11. Laser AI: www.laser.ai/pricing